Subject: UF Radiology Research Newsletter – June Highlights (Publications of the Month)
Dear Colleagues,
We are pleased to share this month’s notable publications from the Department of Radiology at the University of Florida. Below are the June Publications of the Month (POM), each accompanied by a brief summary and a direct link for easy access.
1. Bronchonodal fistula: An uncommon complication of tuberculosis
Journal: Revista da Sociedade Brasileira de Medicina Tropical
🔗 DOI: 10.1590/0037-8682-0127-2025
https://pubmed.ncbi.nlm.nih.gov/42307392/
This case report describes bronchonodal fistula, a rare but clinically significant complication of pulmonary tuberculosis. Through imaging findings and clinical correlation, the authors highlight the importance of recognizing this uncommon manifestation, which can complicate disease progression and management.
The report emphasizes the critical role of thoracic imaging in the early diagnosis of rare tuberculosis complications, facilitating timely treatment and helping clinicians distinguish bronchonodal fistula from other causes of persistent respiratory symptoms.
2. Comparison between Dark-Blood LGE Sequence and Standard Bright-Blood LGE in the Assessment of Ventricular Myocardial Scarring: A Systematic Review and Meta-Analysis
Journal: Radiology: Cardiothoracic Imaging
🔗 DOI: 10.1148/ryct.250567
https://pubmed.ncbi.nlm.nih.gov/42274321/
This systematic review and meta-analysis compares dark-blood and conventional bright-blood late gadolinium enhancement (LGE) cardiac MRI techniques for detecting ventricular myocardial scar. The analysis demonstrates that dark-blood LGE improves scar conspicuity by enhancing the contrast between scar tissue and the blood pool, leading to improved visualization of subendocardial infarcts.
The findings support the growing adoption of dark-blood LGE as an advanced cardiac MRI technique that may improve diagnostic confidence and accuracy in evaluating myocardial fibrosis and ischemic heart disease.
3. Using cell-free DNA tumor methylation score to detect and monitor cholangiocarcinoma
Journal: HPB (Oxford)
🔗 DOI: 10.1016/j.hpb.2026.05.004
https://pubmed.ncbi.nlm.nih.gov/42259736/
This study evaluates the use of a cell-free DNA tumor methylation score as a noninvasive biomarker for the detection and longitudinal monitoring of cholangiocarcinoma. The results demonstrate that methylation profiling of circulating tumor DNA can distinguish patients with cholangiocarcinoma and may provide a sensitive approach for assessing disease burden over time.
The authors highlight the potential of liquid biopsy to complement conventional imaging and clinical evaluation, supporting earlier diagnosis and more effective monitoring of treatment response and disease recurrence in patients with biliary tract malignancies.
4. High Prevalence of Metabolic Dysfunction-Associated Steatohepatitis With Significant Fibrosis in Primary Care and Endocrinology Clinics
Journal: Diabetes, Obesity and Metabolism
🔗 DOI: 10.1111/dom.70799
https://pubmed.ncbi.nlm.nih.gov/42056678/
This study demonstrates a high prevalence of metabolic dysfunction-associated steatohepatitis (MASH) with clinically significant fibrosis among patients seen in primary care and endocrinology clinics. The findings underscore the substantial burden of undiagnosed advanced liver disease in individuals with obesity, type 2 diabetes, and metabolic syndrome.
The authors emphasize the importance of early screening and noninvasive fibrosis assessment in high-risk populations, particularly within frontline outpatient settings where metabolic disease is commonly managed. The work supports broader implementation of multidisciplinary strategies aimed at earlier detection and intervention to reduce progression to cirrhosis and liver-related complications.
We congratulate all authors for their outstanding contributions and look forward to continued innovation in the months ahead.
Kind regards, UF Radiology Research Division